Polymorphism screening services
What we offer:
Crysforma offers complete scientific support to discover and characterize the most relevant polymorphs, hydrates and amorphous phases of a drug and to select the candidate with optimal solid state properties.
Crysforma has developed its own crystallization screening methodology based in the use of several crystallization procedures, oriented to obtain the thermodynamically stable phase as well as kinetically favoured phases. Moreover, solvent-mediated as well as solvent-free crystallization procedures are assayed.
Type of studies:
■Initial or fast polymorphism screening for early stages candidates
■Comprehensive polymorphism study of a drug substance
■Determination of the relative stability of different polymorphs
■Scale-up of selected polymorphs
■Development of analytical methods for polymorph quantification
■Fast powder X-ray diffraction analysis characterization
What are we looking for:
We are looking for pharmaceutical companies (either originator or generic) or fine chemicals companies that are interested in outsourcing polymorphism screening projects, or need to solve problems in the general area of polymorphism or solid state development.
- ] Agrochemicals
- ] Organic substances
- ] Pharmaceutics
- ] Special Chemicals, intermediates
- ] Analytical chemistry
- Research and development
- Technical Co-operation