List of participants

Passive sampler for monitoring atmospheric pollutants (VERAM)

Researchers from University of Valencia have developed a fast, easy and versatile monitoring protocol for organic contaminants in air, based on the development of a new passive sampler (VERAM). This device consists of a lay-flat low-density polyehytelene membrane filled with solid phases. Retained pollutants are directly determined by gas chromatography (GC) using head space injection (HS) after heating the sampling device. The great advantages include the absence of sample handling, the reduction of analysis time and the avoidance of the use of solvents. A mixture of different solid phases allows sample all the possible pollutants in the air or it is possible to select appropriated solid phases for a specific sampling of compounds as a function of their physical-chemical properties.

We are looking for potential licensees and/or companies interested in VERAM fabrication in Spain

• ] Analytical chemistry
• ] Environment

• Licence Agreement
• Manufacturing Agreement
• Research and development

Analysis and design of cosmetic products

GICAPC (Research group for analytical control of cosmetic products) is a research group of the University of Valencia, being its activity focused on:
-design, optimization and validation of analytical methods for cosmetic components in all kinds of commodities or cosmetic products (sunscreen formulations, shampoos, lipsticks, perfums, etc)
-design, optimization, validation and application of analytical methods for other cosmetic studies (i.e, design of new formulations, cosmetic controls, etc.) using green analytical strategies
-efficacy studies for sun protection products
-studies related to security of cosmetic products
-accumulation studies of some cosmetic ingredients, classified as emerging contaminants, in the environment

The research group seeks for cooperation agreements with companies from the cosmetic sector or any kind of companies interested.
The group is also interested in finding partners for other potential collaborations for contracts or projects R&D regional or national calls and European projects.

• ] Care, hygiene, beauty
• ] Analytical chemistry

• FP7 Project
• Research and development
• Technical Co-operation

Quality studies in fruit juices and other food liquids after different preservation treatments (pasteurization, pulsed electric fields, etc.) and storage conditions

Nutrialiment is a research group of the University of Valencia, being its research activity focused on:
-analysis of physicochemical properties of foods
-minerals determination in waters and foods
-colour analysis in liquid and solid foods
-antioxidant capacity determination in foods
-study of the nutritional quality of food after different preservation and storage treatments
-vitamin content analysis
In brief, the group is able to evaluate food quality parameters for food liquids as fruit juices, vegetable juices, milk, etc.

The research group seeks for cooperation agreements with companies from the food sector or any kind of companies interested.
The group is also interested in finding partners for other potential collaborations for contracts or projects R&D regional or national calls and european projects.

• ] Food additives / Ingredients / Fuctional Food

• FP7 Project
• Research and development
• Technical Co-operation

Control system for the biological nitrogen removal in wastewater treatment plants based on low-cost sensors

Researchers from University of Valencia and Polytechnic University of Valencia have developed a control system for continuous WWTPs with biological nitrogen removal using low-cost sensors such as pH and ORP sensors. pH and ORP measurements give valuable information for applying fuzzy logic-based controllers. This control system let optimize the activated sludge process since maintains effluent nitrogen concentration under limit values with lower energy consumption. Moreover, with the obtained results, aeration and pumping energy consumption are optimized. This control system is programmed in a dedicated control application and can be installed to the control PC of the WWTP where it is connected to the SCADA of the plant by using standard OPC communication protocol.

We are looking for potential licensees or commercial agreements with technical assistance with companies focused on wastewater treatment.

• ] Environment
• ] Waste management

• Commercial Agreement
• FP7 Project
• Licence Agreement
• Research and development
• Technical Co-operation

Metal complexes with antioxidant activity

Researchers from University of Valencia have synthesized new SOD mimetic metal complexes which could be used as active ingredients in pharmaceutical compositions or food additives. These complexes present a high superoxide dismutase-like activity with low values of IC50, what supposes that the required quantity of complex to cause the mimetic/antioxidant effect is smaller that for other described synthetic compounds, and therefore possible side effects will be reduced. Moreover, these new complexes show high stability and low toxicity, what makes them good candidates for the treatment of diseases based on alterations or lacks of the SOD activity.

Licence Agreement or R+D agreements with pharmaceutical firms and/or drug development companies for carrying out preclinical and clinical development phases, needed for the development and final exploitation of the compounds.

• ] Pharmaceutics
• ] Food additives / Ingredients / Fuctional Food

• Licence Agreement
• Research and development

Use of novel silica-coated silver nanoparticles as cytotoxic agents

Researchers from University of Valencia have developed a new type of silver nanoparticles coated with a silica nano-shell, able to exert selective killing of bacteria by irradiating at their surface plasmon frequency. The nanoparticles bind readily to the surface of bacteria without affecting their growing, since the toxic silver core is covered by the inert silica shell. Upon exposure to light corresponding to the absorption band of the silver nanocore, bacterial death is triggered effectively and selectively, most likely due to the enhanced electromagnetic fields in the nanoparticle proximity. The main application of the technology is in biomedicine, in phototherapy methods for the treatment of infectious illnesses through the inducement of cell death.

We are looking for potential licensees for the patent in Spain

• ] Pharmaceutics
• ] Biology/Biotechnology
• ] Micro- and Nanotechnology

• Licence Agreement
• Research and development

Micro-chamber device for cellular culture monitoring by nuclear magnetic resonance

The object of this invention is a compact (encapsulated) micro-chamber for longitudinal long-term studies of cellular systems by means of nuclear magnetic resonance (NMR). It can be placed in commercially available NMR equipment. It is made with biocompatible and transparent materials, which allows complementary microscopy monitoring, using equipment for other microscopic techniques. It has been designed as a device for an easy use, not requiring laborious manipulation. Image analysis and metabolic studies of different cellular systemscan be carried out, using the appropriate conditions for each type of cell. Different channels are built and used for the independent insertion of cells, culture medium, and several sensors to control physical-chemical properties.

We are looking for potential licensees for the patent

• ] Pharmaceutics
• ] Biology/Biotechnology

• Licence Agreement
• Research and development

New method for the production of metallic oxides with spinel structure

Researchers of the Institute of Molecular Science of the University of Valencia have developed a new procedure for the synthesis of spinels from water soluble precursors. This procedure is faster, with lower energy consumption and generates purer spinels than known methods for spinel production. The main applications of the technology are:
-in ceramic industry, for the development of new pigments as ceramic water-soluble inks, because of the colour, purity and high temperature stability of the produced spinels
-in electronic industry, for the development of electronic components (i.e. high density memories) by applying water-soluble inks in nanolithography

We are looking for potential licensees of the technology.

• ] Materials technology
• ] Colours, dyes related to Chemicals technology and engineering

• Licence Agreement
• Research and development

Control and design of detergents, vegetable oils and cosmetic products

CLECEM (Research group on liquid chromatography, capillary electrophoresis and mass spectroscopy) is a research group of the University of Valencia, being its activity focused on the development of analytical methods for industrial products, including personal care and cleaning products, vegetable oils and essences:
-Composition studies of surfactants, other cleaning additives and major and minor components in vegetable oils
-Quality control of final products and commodities
-Design and characterization of products with reduced environmental impact

The research group seeks for cooperation agreements with companies from the cosmetic or detergent sectors or any kind of companies interested.
The group is also interested in finding partners for other potential collaborations for contracts or projects R&D regional or national calls and European projects.

• ] Soaps, detergents
• ] Care, hygiene, beauty
• ] Analytical chemistry

• FP7 Project
• Research and development
• Technical Co-operation

Charge injection layer for electro-optical devices (OLEDs)

Researchers of the Institute of Molecular Science of the University of Valencia have developed a new charge injection layer for electro-optical devices, from metallic conductors to semiconductor or insulating materials based on organic or inorganic molecules and macromolecules with electrical or optical properties. With the proposed OLED is possible more light generation per current unit, as well as generating light at lower voltages, which results in a more energy-efficient devices.
The main applications of the technology are in lighting technology( large panels or wallpaper of light for signage or decoration, folded panels or even in clothing) and in electronic display applications (mobile phones, mp3 players ,TV, etc)

We are looking for potential licensees for the patent in Spain

• ] Coatings
• ] Surface treatment
• ] Materials technology

• Licence Agreement
• Research and development

Use of the PEDF factor to induce stem cells self renewal

Researchers at the University of Valencia and the University of Castilla La Mancha have developed a new method to induce stem cells self-renewal, through the use of the Pigment Epithelium-Derived Factor (PEDF). PEDF keeps stem cells plastic properties and their undifferentiated state through a moderated proliferation process, which attends to natural signals of growth. Thus, an excessive expansion is avoided, restricting the appearance of undesired effects, such as tumours, and/or the culture’s exhaustion. As a result, an increase of the cell culture’s efficiency and therapeutic potential is reported, achieving a higher yield in the production of stem cells from an initial amount. The capacity of self-renewal induction has been tested in vitro and in vivo, in mice neural cells. The main applications of the technology are in cell biology and regenerative medicine.

We are looking for potential licensees or R+D agreements with companies focused on cell biology or regenerative medicine.

• ] Pharmaceutics
• ] Biology/Biotechnology

• Licence Agreement
• Research and development

Method for producing nanocorundum

Researchers fromUniversity of Valencia have developed a novel method for producing corundum of low crystallinity (nanocorundum) using natural or synthetic commodities in solid state, without pretreatment. The method of the invention produces nanocorundum, avoiding the formation of alumina transition polymorphs of low temperature. As a result, the final product is porous and their disintegration is easy, avoiding the hardness and difficult grinding of the compact corundum. The main application of the technology is in the chemical industry, for producing corundum for diverse uses (refractories, abrasives, functional fillers for polymers, production of ceramics, glasses and glazed ceramics with reactive alumina, etc) and nanocorundum for special applications (catalyst carriers, implants, aerospace applications, etc.).

We are looking for licensees for the patent and potential collaborations for contracts or projects.

• ] Materials technology
• ] Micro- and Nanotechnology

• Licence Agreement
• Research and development

New method for the synthesis of inert metallic nanoparticles

Researchers from Molecular Science Institute (ICMUV)-University of Valencia have developed a new procedure for the synthesis of inert metallic nanoparticles in only one step. This method makes possible the production of nanoparticles in a rapid way, at low temperature and controlling size, morphology and concentration of nanoparticles. These obtained nanoparticles can be used in:
-cosmetics, for improving compounds bioavailability
-pharmaceutics, for improving drug delivery
-biotechnology, for tracing and functionalizing organic molecules and for the development of biosensor, applying surface plasmon resonance (SPR) properties of metallic nanoparticles
-chemistry and petrochemistry, as catalyzers

We are looking for potential licensees for the patent in Spain

• ] Pharmaceutics
• ] Petrochemistry, Petroleum Engineering
• ] Biology/Biotechnology
• ] Micro- and Nanotechnology

• Licence Agreement
• Research and development

Improving nutritional profile of food products

The Bionutest group of the Nutrition and Food Chemistry Area of the University of Valencia offers its knowledge and expertise to companies with the aim of improving the nutritional profile of their food products by means of an adequate development of quality controls and functional evaluations. The main technological services offered by the group are focused on:
-In vitro bioavailability of foods components (nutrients and bioactive compounds)
-Application of spectrometry, liquid chromatography, gas chromatography mass spectrometry to food components determination
- Biological effects of food components by in vitro techniques using cell cultures
-Determination of lipid and protein quality parameters of foods
-Nutritional evaluation of food composition

The research group seeks for cooperation agreements with companies from the food sector or any kind of companies interested.
The group is also interested in finding partners for other potential collaborations for contracts or projects R&D regional or national calls and european projects.

• ] Food additives / Ingredients / Fuctional Food

• FP7 Project
• Research and development
• Technical Co-operation

Magnetic in-tube solid phase microextraction (MAGNETIC-IT-SPME)

Researchers from University of Valencia have developed a new procedure and device for in-tube solid phase microextraction (IT-SPME) which shows better extraction efficiency than current systems by using magnetic nanoparticles (MNPs) in the adsorbent phase in the capillary and applying an external magnetic field.
The new device MAGNETIC-IT-SPME, connected to a capillary liquid chromatography dispositive, will be valuable for the execution of fully automated chemical analysis if high sensibility is required.

We are looking for potential licensees of the technology.

• ] Analytical chemistry
• ] Separation Technologies
• ] Micro- and Nanotechnology

• Licence Agreement
• Research and development

Immunoassays for the determination of fungicide residues

Researchers from University of Valencia and CSIC have synthesized haptens to generate antibodies for the immunochemical determination of fungicides such as boscalid and cyprodinil. These antibodies can be included in an immunoassay kit for a sensible and fast detection of fungicide residues. Immunoassays offer the possibility of rapid determination, both qualitatively and quantitatively, of trace levels of pesticides in food and environmental matrices. Moreover, researchers are able to obtain effective antibodies against other compounds, not only against boscalid and cyprodinil.

We are looking for licensees for patents and potential collaborations for contracts or projects.

• ] Biology/Biotechnology
• ] Pesticides
• ] Environment

• Licence Agreement
• Research and development